| Formalities On-Line |  |
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GI-1597
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DISCOVERY AND SYNTHESIS OF DRUGS [4619]
Group info
| Code: |
GI-1597 |
| Short Name: |
Desinfarma |
| Name: |
Discovery and Synthesis of Drugs |
| Department: |
Centro de Investigación en Química Biolóxica e Materiais Moleculares (CIQUS) |
| Web: |
https://www.sotelolab.es
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| Contact: |
SOTELO PEREZ, EDDY - e.sotelo@usc.es
Telf.
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Research field - Synthesis of novel proline related peptidomimetics with neuroprotective activity
- Development and exploitation of new synthetic methodologies in Combinatorial Chemistry. Multicomponent Reactions
- Design, Synthesis and Structure-Activity Relationship of heterocyclic compounds libraries with diverse farmacological activities
- Design and synthesis of novel farmacological tools for the study of complex targets: Fluorescent Ligands, Homo- and Heterobivalent Ligands
- Design, synthesis and evaluation of novel rasagiline related neuroprotective agents
- Asymmetric induction in aza-Diels-Alder reactions with azadienophiles
- Asymmetric drug synthesis and enantiospecific modulation of biological targets: applications in the treatment of neurodegenerative pathologies.
- Control of selectivity in C-C bond formation reactions and study of the structure, stability and reactivity of polyfunctionalized organolithium compounds.
Technology services - Preparation and characterization of novel synthetic molecules.
- Design and synthesis of libraries of small molecules for pharmacological screening and for the study of complex biological systems.
- Synthesis of new heterocyclic systems for their use as novel scaffolds.
- Preparation of chemical libraries for Lead Generation and/or Lead Optimisation.
- Development and optimization of novel processes of organic synthesis
Key words - Drugs for neurodegenerative pathologies; Cancer immunotherapy; Enantiospecific recognition in biological targets; GPCR´s modulation; Adenosine receptor antagonists; Aza-Diels Alder reactions; Peptidomimetics; Neuroprotection; Combinatorial chemistry; Chemotherapeutics; Multicomponent reactions.
Researchers | Name | Position | PIID | ORCID | Contact: | | SOTELO PEREZ, EDDY | Coordinador | 60419 | 0000-0001-5571-2812 | E-Mail: e.sotelo@usc.es
| | GARCIA MERA, XERARDO XUSTO | Membro | 59095 | 0000-0001-5218-6351 | | | PALEO PILLADO, MARIA RITA | Membro | 59824 | | | | SELAS LANSEROS, ASIER | Membro | | | | | ANDUJAR ARIAS, ANTONIO | IFP | | | | | CAMPOS PRIETO, LUCIA | IFP | | | | | FOJO CARBALLO, HUGO | IFP | | | | | GARCIA REY, AITOR | IFP | | | | | GARCIA REY, AITOR | IFP | | | | | González Pico, Lucía | IFP | | | | | MIRANDA PASTORIZA, DARIO | IFP | | | | | Ortigueira Noya, Sandra | IFP | | | | | RODRIGUEZ GARCIA, CARLOS | IFP | | | | | RODRIGUEZ GARCIA, CARLOS | IFP | | | | | REZA RAMOS, DAVID | PA | | | | | | | | | | IP Principal Investigator, IFP Training Research, PA Supporting Researchers and Technicians | External collaborators | Name | Institution | | FRANCO FERNANDEZ GONZALEZ | Universidad de Santiago de Compostela | | Hugo Gutiérrea de Terán | Uppsala University | | JOSE ENRIQUE RODRIGUEZ BORGES | Universidade do Porto | | Johny Alberto Azuaje Guerrero | Oncostellae S.L | | LUZ ELIZABETH ESCALANTE ESCALANTE | Oncostellae S.L | | Angela Stefanachi | University of Bari | | Ana Oliveira | Oporto University | | MARIA MAJELLARO | Celtarys Research | | Marialessandra Contino | University of Bari |
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