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GI-1682 - MARINE TOXINS: MECHANISM OF TRANSDUCTION, THERAPEUTIC USES AND DETECTION METHODS

Group info
Code: GI-1682
Short Name: FARMATOX
Name: Marine toxins: Mechanism of transduction, therapeutic uses and detection methods
Department: Departamento de Farmacoloxía, Farmacia e Tecnoloxía Farmacéutica
Web: http://www.detectox.eu/pharmacology.asp
Contact: BOTANA LOPEZ, LUIS MIGUEL - luis.botana@usc.es
Telf.982-252242
Fax: 982-252242
Research field
  • Development of functional assays for the rapid detection of marine phycotoxins
  • Antiallergic and antineoplastic drugs, study of their mechanism of action in normal and tumour cells.
  • Antiallergic drugs and signal transduction in mast cells, lymphocytes and intestinal cells.
  • Neurotoxic and paralytic toxic blooms: development of detection methods, toxicological studies.
  • Toxic blooms of diarrhoeic and liphophylic nature: development of biochemical and functional detection, study of their toxicity and their pharmacological target.
  • Development of functional methods of the absortion in intestine.
  • Development of optical biosensor-based methods for phycotoxins.
Technology services
  • Development of kits to detect phycotoxins.
  • Identification of pharmacological activities in screening and HTS
Key words
  • Mast cell, Lymphocyte, Phycotoxin, Allergie, Transduction signal, Cancer, Okadaic, Saxitoxin, Yesotoxin, Palitoxin, Enterocyte
Researchers
Name Position ORCID Contact:
BOTANA LOPEZ, LUIS MIGUELCoordinador0000-0003-2153-6608Tel./Ext.: 982-252242
Fax: 982-252242
E-Mail: luis.botana@usc.es
ALFONSO RANCAÑO, MARIA AMPAROMembro0000-0003-1572-9016
BOTANA LOPEZ, ANA MARIAMembro
CARRERA GONZALEZ, MARIA CRISTINAMembro
LOUZAO OJEDA, Mª CARMENMembro
RODRIGUEZ VIEYTES, MARIA MERCEDESMembro
VALE GONZALEZ, MARIA DEL CARMENMembro0000-0002-9842-6223
VILARIÑO DEL RIO, NATALIAMembro0000-0001-6055-6359
ABAL CAMAÑO, PAULAIFP
ALVARIÑO ROMERO, REBECAIFP
BOENTE JUNCAL, ANDREAIFP
GEGUNDE MOSQUERA, SANDRAIFP
GONZALEZ JARTIN, JESUSIFP
IP Principal Investigator, IFP Training Research, PA Supporting Researchers and Technicians
External collaborators
Name Institution
Juan Manuel Vieítes Baptista de Sousa  ANFACO-CECOPESCA
Jordi Molgo   Institut Fédératif de Neurobiologie Alfred Fessard
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