Evaluation of new molecules effectives in the treatment of neurodegenerative diseases (Parkinson, Alzheimer, etc.)
Evaluation of new molecules effectives in the treatment of psycologic - psychiatric disorders (ansiolytics, sedatives, antidepressives, antipsychotics, etc.)
Oxidative stress and cytotoxicity
Vasoactive and antithrombotic drugs
Technology services
Isolated and thermostathed laboratory to the accomplishment of studies of motor activity (video-recorded), motor coordination (rotating-rod), rotations (rota-count), avoidance-escape (shuttle box), etc.
Neurochemical studies (dopamine, serotonine, etc.) "ex vivo" and "in vivo" by HPLC/EC
Receptors binding studies.
Pharmacological evaluation of antioxidant, cytoprotective, vasoactive, and platelet antiaggregant drugs. The appropiate recurses to carry out the studies are available (spectrophotometer, organ bath, aggregometer, etc.)
Key words
Pharmacology of central nervous system (CNS); Neuropsycopharmacology; Neurotoxicity; Parkinson; Alzheimer;
Psychosis; Anxiety; Depression; Oxidative stress; Reactive oxygen species (ROS); Cerebrovascular diseases
