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GI-2155 - ENZYME INHIBITORS AND CHEMICAL TOOLS IN BIOLOGY

Group info
Code: GI-2155
Short Name: INCTB
Name: Enzyme Inhibitors and Chemical Tools in Biology
Department: Departamento de Química Orgánica
Web: http://www.usc.es/ciqus/en/groups/gonzalezbello
Contact: GONZALEZ BELLO, CONCEPCION - concepcion.gonzalez.bello@usc.es
Telf.

Research field
  • Development of novel antimicrobial agents with a new mechanism of action for the treatment of resitant bacterial diseases.
  • Computational studies of enzymatic catalysis and molecular recognition as the basis of ligand design: Molecular Dynamics, QM/MM
  • DNA recognition agents, molecular sensors and devices
  • Chemical tools to study mitochondria
  • Development of "IC-tagging" for the production of subunit vaccines
Technology services
  • Synthesis of highly functionalized organic compounds
  • Prediction of the interaction ligand-biomacromolecule by molecular docking
  • Molecular Dynamics simulations of enzyme/ligand and protein/ligand complexes
  • Synthesis of peptides and coordination complexes
  • Photochemistry and circular dichroism
  • Protein expression
  • Virology
  • Biotechnology
Key words
  • enzyme inhibitors, enzymatic catalysis, docking and Molecular Dynamics, Fluorescence,Peptides, Helicates, Molecular sensors and devices, patogenesis molecular, viroplasmas, molecular weapons, vaccine tools, gene delivery tools
Researchers
Name Position ORCID Contact:
GONZALEZ BELLO, CONCEPCIONCoordinador0000-0001-6439-553XE-Mail: concepcion.gonzalez.bello@usc.es
DIAZ JULLIEN, CRISTINAMembro0000-0002-4307-8129
MANEIRO REY, MARIAMembro0000-0001-6229-9157
MARTINEZ COSTAS, JOSE MANUELMembro0000-0002-8877-7775
RAMA MARTINEZ, GUSTAVOMembro0000-0003-1689-7775
VAZQUEZ LOPEZ, MIGUELMembro0000-0003-3376-3461
VAZQUEZ SENTIS, MARCO EUGENIOMembro0000-0001-7500-985X
ALCALDE ORDOÑEZ, ANAIFP
BOUZADA REBOREDO, DAVIDIFP0000-0001-8651-1052
CANABAL FALCON, RAFAELIFP0000-0002-4962-6050
COLCHON PIERNA, ESTHERIFP0000-0002-3411-1740
Gerpe Amor, TaniaIFP0000-0003-0601-3892
GOMEZ GONZALEZ, JACOBOIFP
López Ferrón, AlejandroIFP
RODRIGUEZ COSTA, ANGELAIFP0000-0002-6381-0495
BARREIRO PIÑEIRO, NATALIAPA
LENCE QUINTANA, EMILIO JOSEPA0000-0001-9489-9421
POSE BOIRAZIAN, TOMASPA
IP Principal Investigator, IFP Training Research, PA Supporting Researchers and Technicians
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