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GI-2155 - ENZYME INHIBITORS AND CHEMICAL TOOLS IN BIOLOGY

Group info
Code: GI-2155
Short Name: INCTB
Name: Enzyme Inhibitors and Chemical Tools in Biology
Department: Departamento de Química Orgánica
Web: http://www.usc.es/ciqus/en/groups/gonzalezbello
Contact: González Bello, Concepción - concepcion.gonzalez.bello@usc.es
Telf.

Research field
  • Development of novel antimicrobial agents with a new mechanism of action for the treatment of resitant bacterial diseases.
  • Computational studies of enzymatic catalysis and molecular recognition as the basis of ligand design: Molecular Dynamics, QM/MM
  • DNA recognition agents, molecular sensors and devices
  • Chemical tools to study mitochondria
  • Development of "IC-tagging" for the production of subunit vaccines
Technology services
  • Synthesis of highly functionalized organic compounds
  • Prediction of the interaction ligand-biomacromolecule by molecular docking
  • Molecular Dynamics simulations of enzyme/ligand and protein/ligand complexes
  • Synthesis of peptides and coordination complexes
  • Photochemistry and circular dichroism
  • Protein expression
  • Virology
  • Biotechnology
Key words
  • enzyme inhibitors, enzymatic catalysis, docking and Molecular Dynamics, Fluorescence,Peptides, Helicates, Molecular sensors and devices, patogenesis molecular, viroplasmas, molecular weapons, vaccine tools, gene delivery tools
Researchers
Name Position ORCID Contact:
González Bello, ConcepciónCoordinador0000-0001-6439-553XE-Mail: concepcion.gonzalez.bello@usc.es
Díaz Jullien, CristinaMembro0000-0002-4307-8129
Maneiro Rey, MaríaMembro
Martínez Costas, José ManuelMembro0000-0002-8877-7775
Rama Martínez, GustavoMembro
Vázquez López, MiguelMembro
Vázquez Sentís, Marco EugenioMembro0000-0001-7500-985X
Alcalde Ordóñez, AnaIFP
Boga Matos, SoniaIFP
Bouzada Reboredo, DavidIFP0000-0001-8651-1052
Canabal Falcón, RafaelIFP
Colchón Pierna, EstherIFP
Gerpe Amor, TaniaIFP
Gómez González, JacoboIFP
Robles Baños, AdriánIFP
Rodriguez Costa, ÁngelaIFP
Rodríguez Lema, Diana IFP
Barreiro Piñeiro, NataliaPA
Lence Quintana, Emilio JoséPA0000-0001-9489-9421
Pose Boirazian, TomásPA
IP Principal Investigator, IFP Training Research, PA Supporting Researchers and Technicians
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